The American Society of Regional Anesthesia and Pain Medicine present our Regional Anesthesia and Pain Podcast (ASRA RAPP). This podcast is designed to bring you ongoing conversations in this exciting field of medicine throughout the year. The podcast is hosted by Dr. Raj Gupta and Dr. Eric Schwenk but will include many guests from the ASRA community. We will discuss current topics in both regional anesthesia and pain medicine, we will invite authors of significant publications to help explain their work, we will debate the merits and pitfalls of new technology and therapy, and we will inform you about important events where you can participate with the ASRA community in person. Join in the conversation with ASRA!

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Episode 14: Additives for Peripheral Nerve Blocks

Updated about 5 days ago.

Raj Gupta (@dr_rajgupta) and Eric Schwenk (@ESchwenkMD) discuss the value and risks of additives used to extended analgesia with peripheral nerve blocks. Our guests for this show are Chad Brummett (@drchadb) from the University of Michigan and Brian Williams ( from the University of Pittsburgh Medical Center and the VA Pittsburgh Healthcare System. Recorded 08/10/2017.
Thanks to The Preps from Philadelphia, PA for the music: “The Grind (9 to 5)" and "Unknown Night". The band features Steve Breslin on vocals/guitars, Bryan Schwenk on guitars/vocals, Jeff Frederick on bass, and Eric Schwenk on drums.
Selected References:

1. Brummett, C. M., & Williams, B. A. (2011). Additives to local anesthetics for peripheral nerve blockade. International Anesthesiology Clinics, 49(4), 104–116.
2. Marhofer, P., & Brummett, C. M. (2016). Safety and efficiency of dexmedetomidine as adjuvant to local anesthetics. Current Opinion in Anaesthesiology, 29(5), 632–637.
3. Williams, B. A., Butt, M. T., Zeller, J. R., Coffee, S., & Pippi, M. A. (2015). Multimodal perineural analgesia with combined bupivacaine-clonidine-buprenorphine-dexamethasone: safe in vivo and chemically compatible in solution. Pain Medicine (Malden, Mass.), 16(1), 186–198.
4. Williams, B. A., Hough, K. A., Tsui, B. Y. K., Ibinson, J. W., Gold, M. S., & Gebhart, G. F. (2011). Neurotoxicity of adjuvants used in perineural anesthesia and analgesia in comparison with ropivacaine. Regional Anesthesia and Pain Medicine, 36(3), 225–230.