Mentors at Your Benchside

A good mentor can be the difference between success and failure. But what to do if you don't have help on hand? Mentors At Your Benchside provides curated help and advice from experienced researchers on various topics, from lab skills and techniques to career progression. Each short episode is bursting with easy-to-access help and advice that can improve your results and help you get the most out of your time in the lab.

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Why Is SDS-PAGE Run Vertically? Here are 3 Great Answers

Updated 2 months ago.

#18 — Why are SDS-PAGE gels run vertically? What would happen if we ran them horizontally? Has anyone ever tried? Discover the answers to these questions and more in this episode of Mentors At Your Benchside.

To see what others are saying and join in the conversation, head over to the comments section in the original article on why SDS-PAGE is run vertically. [1]

If this episode has ignited your desire for answers, Check out some of our related articles to learn the how SDS-PAGE works and discover whether running your SDS-PAGE gels with constant current or constant voltage is best. [2,3]

1. Why Is SDS-PAGE Run Vertically? Here are 3 Great Answers. Available at:
2. How SDS-PAGE Works. Available at:
3. Constant Current or Voltage in SDS-PAGE: The Great Debate. Available at: