Mentors at Your Benchside

A good mentor can be the difference between success and failure. But what to do if you don't have help on hand? Mentors At Your Benchside provides curated help and advice from experienced researchers on various topics, from lab skills and techniques to career progression. Each short episode is bursting with easy-to-access help and advice that can improve your results and help you get the most out of your time in the lab.

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Laemmli Buffer: What Is It for Anyway?

Updated about 1 month ago.

#20 — Have you ever wondered how Laemmli buffer actually works? In this episode of Mentors At Your Benchside, we talk through the different components of Laemmli buffer, what they do and why they are essential for your SDS-PAGE experiments.

Read the full article to learn more about this buffer and get a handy Laemmli buffer recipe. [1]

Looking for more information on SDS-PAGE? Discover the theory behind SDS-PAGE and get advice on how you can cast the perfect SDS-PAGE gel. [2,3] You can also download our useful SDS-PAGE protocol PDF that contains simple buffer recipes, gel recipes, and a neat casting protocol. [4]

1. Laemmli Buffer: What Is It for Anyway? Available at:
2. How SDS-PAGE Works. Available at:
3. A Simple SDS-PAGE Gel Recipe and 10-Step Casting Protocol for Perfect Gels. Available at:
4. Bitesize Bio's SDS-PAGE Protocol PDF Cheat Sheet. Available at: